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TY - UNPB AU - Zheltonozhskaya, M.V. ED - Kuzin, Maksim ED - Schaa, Volker RW TI - Research of 89Zr Output in Photonuclear Reactions on Molybdene J2 - Proc. of RuPAC2018, Protvino, Russia, 1-5 October 2018 C1 - Protvino, Russia T2 - Russian Particle Accelerator Conference T3 - 26 LA - english AB - In recent years, the use of electron accelerators for the production of radiopharmaceuticals has become important and relevant. One of attractive methods for non-invasive tumor detection and treatment planning is the positron emission tomography with radiolabeled monoclonal antibodies. Zr-89 has appropriate decay characteristics for high resolution PET imaging. Usually production of this nuclide is based on (p,n)-reaction on natural yttrium. However, proton accelerators are complex and power-consuming installations. They require a large number of specialists for their maintenance. At the same time, electron accelerators, such as microtrones, are more compact equipment and have undeniable advantages in ease of maintenance and energy costs. Therefore, we are conducting studies of the Zr-89 output in different photonuclear reactions. One of the perspective direction is the use of natural molybdenum as targets for these purposes. When the target is irradiated with high-energy gamma quanta, the short-lived nuclides Mo-89 (T1/2 = 2 min) and Nb-89 (T1/2 = 2 hours) are formed in the reaction (gamma, 3n) and (gamma, p2n), which decay into Zr-89 (T1/2 = 3.3 days). We irradiated the natural molybdenum target on the pulsed microtron with an electron energy 55M eV. The 50 mg target was irradiated during 80 minutes. The average current was 40-45 nA. The spectrometric measurements were carried out using a Canberra semiconductor spectrometer with a detector of high-purity germanium of large volume with an energy resolution 1.8 keV of 1332 keV Co-60 gamma-line. An activity of 240 ± 20 Bq was obtained. The Mo-99 gamma-ray transitions in the (gamma, n)-reaction at Mo-100 were observed in the spectrum. It was found that (gamma, 3n)-reaction cross-section amounts to (1,71±0,08)*10⁻² of (gamma, n)-reaction cross-section. Obtained data is discussed. PB - JACoW CP - Geneva, Switzerland ER -