RUPAC2012 - List of Authors (Fadeev, A.M.)

Paper	Title	Page
WEPPC037	Cylindrical Phased Dipoles Array for Hyperthermia of Deep-Situated Tumors	521
	A.M. Fadeev, V.N. Belyaev, S.M. Polozov MEPhI, Moscow, Russia E.A. Perelstein JINR, Dubna, Moscow Region, Russia
	The treatment of deep-situated malignant tumors is often a difficult problem in which the purpose is to reduce the size of completely remove a tumor by using one or more modalities. The traditional methods are: radiation therapy, chemotherapy and surgery. Hyperthermia is another method which is used alone or coupled with other methods of cancer treatment. Hyperthermia is a heating of the tumor that makes it more sensitive to chemotherapy or radiation therapy and leads to it thermal damage. Temperature range for hyperthermia treatment is from 42.5 C to 45 C. It is important to prevent heating of healthy tissues and to produce sufficient heating at the site of a deep-situated tumor. This kind of hyperthermia is called the local hyperthermia. The electromagnetic field in 100-200 MHz frequency range is optimal for heating of deep-situated tumors. The system for local hyperthermia of cancer was simulated. This system is based on cylindrical phased array consisting of multiple dipole antennas with operating frequency 150 MHz. The electric fields and specific absorption rate distributions are calculated in cut of tissue-equivalent phantom. Shown that electric field can be focused in desirable region by means of varying of amplitudes and phases of each dipole. The advantages of using combined therapy of common hyperthermia with chemotherapy or radiation therapy are discussed.

WEPPC038	RF Power and Control Systems for Phased Dipoles Array System for Hyperthermia	524
	A.M. Fadeev, V.N. Belyaev, A.A. Blinnikov, S.M. Polozov MEPhI, Moscow, Russia E.A. Perelstein JINR, Dubna, Moscow Region, Russia
	Cylindrical array of independently phased dipoles is suggested for hyperthermia of deep-situated tumors as a kind of treatment of cancer coupled with other methods such as radiation therapy and chemotherapy. It was proposed to focus the maximum of electromagnetic field at the site of tumor to produce high efficiency heating of tumor and to prevent overheating of surrounding healthy tissues. That's why we use system of independently fed dipole antennas. The operating frequency is 150 MHz. The independent feeding permits us to focus electromagnetic field producing by phased array in desirable area by means of changing of amplitudes and phases of each dipole. The RF power system schematic layout for 8 independently phased dipole antennas is presented. The control system of RF power system elements is considered. The software developing to provide choosing amplitude's and phase's values of dipoles are discussed.

Paper

Title

Page

Cylindrical Phased Dipoles Array for Hyperthermia of Deep-Situated Tumors

521

A.M. Fadeev, V.N. Belyaev, S.M. Polozov
MEPhI, Moscow, Russia
E.A. Perelstein
JINR, Dubna, Moscow Region, Russia

The treatment of deep-situated malignant tumors is often a difficult problem in which the purpose is to reduce the size of completely remove a tumor by using one or more modalities. The traditional methods are: radiation therapy, chemotherapy and surgery. Hyperthermia is another method which is used alone or coupled with other methods of cancer treatment. Hyperthermia is a heating of the tumor that makes it more sensitive to chemotherapy or radiation therapy and leads to it thermal damage. Temperature range for hyperthermia treatment is from 42.5 C to 45 C. It is important to prevent heating of healthy tissues and to produce sufficient heating at the site of a deep-situated tumor. This kind of hyperthermia is called the local hyperthermia. The electromagnetic field in 100-200 MHz frequency range is optimal for heating of deep-situated tumors. The system for local hyperthermia of cancer was simulated. This system is based on cylindrical phased array consisting of multiple dipole antennas with operating frequency 150 MHz. The electric fields and specific absorption rate distributions are calculated in cut of tissue-equivalent phantom. Shown that electric field can be focused in desirable region by means of varying of amplitudes and phases of each dipole. The advantages of using combined therapy of common hyperthermia with chemotherapy or radiation therapy are discussed.

WEPPC038

RF Power and Control Systems for Phased Dipoles Array System for Hyperthermia

524

A.M. Fadeev, V.N. Belyaev, A.A. Blinnikov, S.M. Polozov
MEPhI, Moscow, Russia
E.A. Perelstein
JINR, Dubna, Moscow Region, Russia

Cylindrical array of independently phased dipoles is suggested for hyperthermia of deep-situated tumors as a kind of treatment of cancer coupled with other methods such as radiation therapy and chemotherapy. It was proposed to focus the maximum of electromagnetic field at the site of tumor to produce high efficiency heating of tumor and to prevent overheating of surrounding healthy tissues. That's why we use system of independently fed dipole antennas. The operating frequency is 150 MHz. The independent feeding permits us to focus electromagnetic field producing by phased array in desirable area by means of changing of amplitudes and phases of each dipole. The RF power system schematic layout for 8 independently phased dipole antennas is presented. The control system of RF power system elements is considered. The software developing to provide choosing amplitude's and phase's values of dipoles are discussed.