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TY - UNPB AU - Grötzsch, D. AU - Beckhoff, B. AU - Dietrich, P. AU - Jonas, A. AU - Kanngießer, B. AU - Malzer, W. AU - Martyanov, W. AU - Nietzold, C. AU - Nutsch, A. AU - Streeck, C. AU - Unger, W. AU - Witte, K.W. ED - Casas, Joan ED - Schaa, Volker RW ED - Costa, Isidre ED - López, David ED - Prieto, Montserrat TI - Enabling Investigations of Fluids and Fluid - Solid - Interfaces With Soft X-Ray Excitation at UHV Conditions J2 - Proc. of MEDSI2016, Barcelona, Spain, 11-16 September 2016 CY - Barcelona, Spain T2 - Mechanical Engineering Design of Synchrotron Radiation Equipment and Instrumentation Conference T3 - 9 LA - english AB - Capturing biochemical markers by bio-molecular films is one of the most promising approaches for the development of highly sensitive and highly selective diagnosis. In particular, future innovative tools for in vitro or point of care diagnostics are expected to rely on this principle. Analytical techniques which can provide information on coverage, orientation and chemical state of biochemical films are capable of contributing to a purposeful development of such diagnostics. We present fluid cells, which were designed to facilitate the application of soft X-ray spectrometry for the in situ analysis of bio-molecular films at solid-liquid interfaces. It allows for - the analysis through a silicon nitride window with a thickness of about 150 nm - in situ preparation of successive layers by rinsing the window Currently, after the first successful soft X-ray experiments on liquids and gases, we are improving the versatility of the fluid cells. Spectrometry in transmission and in various emission geometries will be feasible. Also transmission- and emission-measurements in parallel are tested. Further control devices for the experimental conditions will be added. PB - JACoW Publishing CP - Geneva, Switzerland ER -