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RIS citation export for THPMP052: Recent Progress in R&D for Ionetix Ion-12SC Superconducting Cyclotron for Production of Medical Isotopes

AU  - Wu, X.
AU  - Alt, D.M.
AU  - Blosser, G.F.
AU  - Horner, G.S.
AU  - Neville, Z.S.
AU  - Paquette, J.M.
AU  - Usher, N.R.
AU  - Vincent, J.J.
ED  - Boland, Mark
ED  - Tanaka, Hitoshi
ED  - Button, David
ED  - Dowd, Rohan
ED  - Schaa, Volker RW
ED  - Tan, Eugene
TI  - Recent Progress in R&D for Ionetix Ion-12SC Superconducting Cyclotron for Production of Medical Isotopes
J2  - Proc. of IPAC2019, Melbourne, Australia, 19-24 May 2019
CY  - Melbourne, Australia
T2  - International Particle Accelerator Conference
T3  - 10
LA  - english
AB  - The Ion-12SC is a sub-compact, 12.5 MeV proton su-perconducting isochronous cyclotron for commercial medical isotope production recently developed at Ionetix Corporation [1]. The machine features a patented cold steel and cryogen-free conduction cooling magnet, a low power internal cold-cathode PIG ion source, and an inter-nal liquid target [2]. It was initially designed to produce N-13 ammonia for dose on-demand cardiology applica-tions but can also be used to produce F-18, Ga-68 and other medical isotopes widely used in Positron Emission Tomography (PET). The 1st engineering prototype was completed and commissioned in September 2015, and four additional units have been completed since [3]. The first two units have been installed and operated at the University of Michigan and MIT. R&D efforts in physics and engineering have continued to improve machine performance, stability and reliability. These improve-ments include: 1) Water cooling added to the dummy dee to limit the operating temperature of the ion source to improve lifetime and performance, 2) Magnetic field maps, obtained with a Hall probe based mapper, were used to accurately measure the isochronism and provide information needed to compensate for any unwanted 1st harmonics and 3) Feedback based control methods ap-plied to regulate the beam intensity on target by adjusting the ion source cathode current. The C1 unit installed at the University of Michigan Medical School early this year treated ~100 patients/month with N-13 ammonia. The machines are now capable of routinely producing > 21 doses/day with > 99% availability. The Ionetix manu-facturing facility is capable of producing up to 30 ma-chines per year.
PB  - JACoW Publishing
CP  - Geneva, Switzerland
SP  - 3568
EP  - 3570
KW  - cyclotron
KW  - ion-source
KW  - target
KW  - controls
KW  - cathode
DA  - 2019/06
PY  - 2019
SN  - 978-3-95450-208-0
DO  - DOI: 10.18429/JACoW-IPAC2019-THPMP052
UR  - http://jacow.org/ipac2019/papers/thpmp052.pdf
ER  -