PAC09 - List of Authors (Lee, S.-K.)

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Lee, S.-K.

Paper	Title	Page
TU6PFP010	Feasibility Studies on the In-Vivo Experiments at the MC-50 Cyclotron Using a Prototype LEPT System	1312
	K. R. Kim, J.-H. Jang, M.H. Jung, S.-K. Lee KAERI, Daejon Y.M. Lee Kyungpook National University, Daegu T.K. Yang KIRAMS, Seoul
	Funding: This work was perfomed as a part of the Proton Engineering Frontier Project and supported by the ministry of Education, Science and Technology of Korea. A prototype LEPT(Low Energy Proton Therapy) system was developed and established at the MC-50 cyclotron in 2007. Some of the users of the PEFP (Proton Engineering Frontier Project) has been requiring a irradiation system for in-vivo experiments for the beam utilization in the fieds of medical and biological sciences. We are studying on the possibility of in-vivo experiments the prototype LEPT system. The LEPT system consists of collimators, range shifter, modulator for SOBP, dose meaurement system, etc. The energy and current from the cyclotron was 45 MeV and a few nA. For the in-vivo experiments accurate control of dose rate and penetration depth range is essential. The other important issue is how we can control the irradiation area and depth with high uniform dose distribution. We investigated the dose rate and uniformity of dose distribution inside the sample using PMMA and water phantom. The dose was measured by using ionization chamber and GAF films. The dose rate was 0.2~1Gy/sec and the penetration depth was 10~15 mm. The further studies using small animals using this LEPT system will be done by the users.

Paper

Title

Page

TU6PFP010

Feasibility Studies on the In-Vivo Experiments at the MC-50 Cyclotron Using a Prototype LEPT System

1312

K. R. Kim, J.-H. Jang, M.H. Jung, S.-K. Lee
KAERI, Daejon
Y.M. Lee
Kyungpook National University, Daegu
T.K. Yang
KIRAMS, Seoul

Funding: This work was perfomed as a part of the Proton Engineering Frontier Project and supported by the ministry of Education, Science and Technology of Korea.

A prototype LEPT(Low Energy Proton Therapy) system was developed and established at the MC-50 cyclotron in 2007. Some of the users of the PEFP (Proton Engineering Frontier Project) has been requiring a irradiation system for in-vivo experiments for the beam utilization in the fieds of medical and biological sciences. We are studying on the possibility of in-vivo experiments the prototype LEPT system. The LEPT system consists of collimators, range shifter, modulator for SOBP, dose meaurement system, etc. The energy and current from the cyclotron was 45 MeV and a few nA. For the in-vivo experiments accurate control of dose rate and penetration depth range is essential. The other important issue is how we can control the irradiation area and depth with high uniform dose distribution. We investigated the dose rate and uniformity of dose distribution inside the sample using PMMA and water phantom. The dose was measured by using ionization chamber and GAF films. The dose rate was 0.2~1Gy/sec and the penetration depth was 10~15 mm. The further studies using small animals using this LEPT system will be done by the users.