| Paper | Title | Page |
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| MO6RFP102 | Present Status of a Multi-Bunch Electron Beam Linac Based on Cs-Te Photo-Cathode RF-Gun at Waseda University | 608 |
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At Waseda University, we have been developing a high quality electron source based on photo-cathode rf-gun and its application experiments. To produce a high current electron beam, we installed a Cs-Te cathode which has higher quantum efficiency and improved the structure of the rf cavity. By adopting a Cs-Te cathode, it is expected that the production of the higher charged single bunch electron beam with a low emittance can be achieved. Moreover, the generation of high quality multi-bunch electron beam is also expected to be possible due to the high quantum efficiency of Cs-Te. For understanding of a Cs-Te cathode and higher quantum efficiency operation, we have performed the fundamental studies by single bunch beam. On the other hand, we have also developed a multi-pulse UV laser for generating the multi-bunch electron beam. Our laser system is composed by all-solid-state Nd:YLF for the stable operation, and the specification of this laser is expected to generate a 100bunch/train with the bunch charge of 800pC/bunch. In this conference, the experimental results of Cs-Te and new laser system and the recent progress of multi-bunch electron beam generation will be reported. |
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| TU6PFP016 | Pinpoint keV X-Ray Imaging for X-Ray Drug Delivery System | 1328 |
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In X-ray Drug Delivery System, anticancer drugs containing Pt, such as cisplatin and dachplatin, and Au colloid contrast agent are surrounded by polymers (micelle, PEG (polyethylene glycol), etc.).Ttheir sizes are controlled to be 20-100 nm. Since holes of capillary to organ are as large as 100 nm in only cancer, those large particles can be accumulated in cancer effectively. That is called as EPR (Extended Penetration and Retention effect). We have observed the distribution of Pt of dachplatin-micelle in cancer of mouse’s pancreas by X-ray fluorescence analysis using 10 μm pinpoint 15 keV X-ray by SPring8. Further, in-vitro- and in-vivo-experiments of Au colloid PEG are under way. It is expected to be used as contrast agent for dynamic tracking treatment for moving cancer. Imaging properties for polychromatic X-rays from X-ray tube and monochromatic Compton source are numerically analyzed and discussed. We continue to analyze radiation enhancement by Auger electrons and successive characteristic X-rays and its toxic effect to cancer. |
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| TU6PFP027 | Improvement of Compact Pico-Second and Nano-Second Pulse Radiolysis Systems at Waseda University | 1345 |
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A pulse radiolysis method is very useful in clarifying primary processes of radiation chemistry. At Waseda University, compact pico-second and nano-second pulse radiolysis systems have been developing. A pico-second system is based on pump-probe method. IR and UV pico-second laser pulses are generated from Nd:YLF mode-locked laser and used for generating of white light continuum as analyzing light and irradiating to photo-cathode RF gun, respectively. Recently, we have installed a new photo-cathode RF gun with Cs-Te cathode which has high quantum efficiency, so we have succeeded in improving optical density and S/N ratio of our pulse radiolysis system. We are now developing a new nano-second system which can get time profile with only one-shot and follow up wider time region than pico-second system. In the past, this system has been used He-Ne laser as analyzing light, but it can measure only 633nm. Instead of He-Ne laser, this system adopts Xe flush lamp which has broad spectrum as analyzing light. As system evaluation experiments, we tried to get time profile of some species. In this conference, present status and future plans of our pulse radiolysis systems will be reported. |