FEL2009 - List of Authors (Shishikura, F.)

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Shishikura, F.

Paper	Title	Page
WEPC27	Visible FEL Irradiation Experiments on Carbonmonoxy Hemoglobin	561
	F. Shishikura, K. Ishikawa Nihon University School of Medicine, Tokyo K. Hayakawa, Y. Hayakawa, T. Kuwada, K. Nakao, K. Nogami, T. Tanaka LEBRA, Funabashi M. Inagaki, T. Sakai, I. Sato Nihon University, Advanced Research Institute for the Sciences and Humanities, Funabashi
	The Free-Electron Laser (FEL) of LEBRA[1] produces near infrared FELs (IR FELs) including tunable wavelength from 1 to 6 microns. The higher harmonics generated by means of the nonlinear optical crystals are also available with output energy of about 0.5 mJ/micro-pulse. The IR FELs of LEBRA are of significant interest because these tunable wavelengths covered with visible and near infrared regions (350 nm-6000 nm) expect to unveil photochemical reactions of bio-macromolecules even in living organisms. We use LEBRA IR FELs for macromolecules such as caronmonoxy hemoglobin (COHb), whose maximum absorption spectra are known as Soret band (418 nm) and two weaker bands (538 nm and 568 nm). We first selected three of the visible wavelengths. After irradiation (up to about 10 J), the each effect of three wavelengths on COHb was separately investigated by several methods icluding visible scanning absorption spectroscopy and Raman microscopy. We report the present results on the mesurements. [1] Laboratory for Electron Beam Research and Application, Institute of Quantum Science, Nihon University.

Paper

Title

Page

WEPC27

Visible FEL Irradiation Experiments on Carbonmonoxy Hemoglobin

561

F. Shishikura, K. Ishikawa
Nihon University School of Medicine, Tokyo
K. Hayakawa, Y. Hayakawa, T. Kuwada, K. Nakao, K. Nogami, T. Tanaka
LEBRA, Funabashi
M. Inagaki, T. Sakai, I. Sato
Nihon University, Advanced Research Institute for the Sciences and Humanities, Funabashi

The Free-Electron Laser (FEL) of LEBRA[1] produces near infrared FELs (IR FELs) including tunable wavelength from 1 to 6 microns. The higher harmonics generated by means of the nonlinear optical crystals are also available with output energy of about 0.5 mJ/micro-pulse. The IR FELs of LEBRA are of significant interest because these tunable wavelengths covered with visible and near infrared regions (350 nm-6000 nm) expect to unveil photochemical reactions of bio-macromolecules even in living organisms. We use LEBRA IR FELs for macromolecules such as caronmonoxy hemoglobin (COHb), whose maximum absorption spectra are known as Soret band (418 nm) and two weaker bands (538 nm and 568 nm). We first selected three of the visible wavelengths. After irradiation (up to about 10 J), the each effect of three wavelengths on COHb was separately investigated by several methods icluding visible scanning absorption spectroscopy and Raman microscopy. We report the present results on the mesurements.

[1] Laboratory for Electron Beam Research and Application, Institute of Quantum Science, Nihon University.